Dosimetric impact of FFF over FF beam using VMAT for brain neoplasms treated with radiotherapy

Abstract Background: This study was conducted to assess the dosimetric impact of FFF beam plans on high-grade brain neoplasms using VMAT technique when compared with FF plans. Material and Methods: Thirty patients neoplasms, who had received radiotherapy retrospectively were selected for this study. All planned 6MV_FF same plan re-optimized 6MV_FFF keeping dose constraint. Radiotherapy distribution planning target volume (PTV) organs at risk (OAR), conformity index (CI), Homogeneity Index (HI), Low in patient (V 5 , V 10 20 30 ), Integral whole body both compared. Results: The PTV coverage OAR’s showed no significant differences between planning. There a reduction average maximum right eye, left optic nerve, nerve beams. low observed Mean Dose. Also, integral beam. Conclusions: Using beams is doable treatment delivery mode may yield similar results which should be confirmed large scale prospective clinical trial.